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Greenlip Mussel Studies
1/25/2008 - Systematic review of the nutritional supplement Perna Canaliculus (green-lipped mussel) in the treatment of osteoarthritis
S. Brien, P. Prescott, B. Coghlan, N. Bashir and G. Lewith From the Department of Primary Care, University of Southampton, Aldermoor Health Centre, Aldermoor Close, Southampton, Hampshire, SO16 5ST and School of Mathematics, University of Southampton, University Road, Southampton, Hampshire SO17 1BJ, UK Abstract Complementary treatments for osteoarthritis (OA) are sought by patients for symptomatic relief and to avoid the iatrogenic effects of non-steroidal anti-inflammatories.
8/1/2007 - Novel anti-inflammatory omega-3 PUFAs from the New Zealand green-lipped mussel, Perna canaliculus
Comp Biochem Physiol B Biochem Mol Biol. 2007 Aug;147(4):645-56. Epub 2007 Apr 14 Treschow AP, Hodges LD, Wright PF, Wynne PM, Kalafatis N, Macrides TA. Natural Products Research Group, School of Medical Sciences, RMIT University, Bundoora, Victoria, 3083, Australia.
6/11/2007 - Immunomodulation of murine collagen-induced arthritis by N, N-dimethylglycine and a preparation of Perna canaliculus
BMC Complement Altern Med. 2007 Jun 11;7:20 Lawson BR, Belkowski SM, Whitesides JF, Davis P, Lawson JW. Department of Biological Sciences, Clemson University, Clemson, SC, USA.
6/1/2006 - Clinical efficacy and tolerance of an extract of green-lipped mussel (Perna canaliculus) in dogs presumptively diagnosed with degenerative joint disease
N Z Vet J. 2006 Jun;54(3):114-8 Pollard B, Guilford WG, Ankenbauer-Perkins KL, Hedderley D. Institute of Veterinary, Animal and Biomedical Sciences, Massey University, Private Bag 11222, Palmerston North, New Zealand.
1/13/2006 - In vitro modulation of inflammatory cytokine and IgG levels by extracts of Perna canaliculus
BMC Complement Altern Med. 2006 Jan 13;6:1 Mani S, Lawson JW. Department of Microbiology and Molecular Medicine, Clemson University, Clemson, SC 29634, USA. BACKGROUND: Inflammation is a predominant characteristic of autoimmune diseases which is characterized by the increased expression of pro-inflammatory cytokines.
6/1/2002 - Improvement of Arthritic Signs in Dogs Fed Green-Lipped Mussel (Perna canaliculus)
The American Society for Nutritional Sciences J. Nutr. 132:1634S-1636S, June 2002 Tiffany Linn Bierer3 and Linh M. Bui EXPANDED ABSTRACT Arthritis is a significant problem in both humans and animals that may occur at any age but is particularly common in older individuals.
9/1/2000 - Anti-inflammatory effects of a stabilized lipid extract of Perna canaliculus
Halpern GM. Allerg Immunol (Paris). 2000 Sep;32(7):272-8 University of California, USA. A lipid-rich extract, prepared by supercritical fluid (CO2) extraction of freeze-dried stabilized NZ green-lipped mussel powder (Lyprinol) has shown significant anti-inflammatory (AI) activity when given to animals and humans.
5/1/1993 - Anti-inflammatory activity of glycogen extracted from Perna canaliculus (NZ green-lipped mussel).
Agents Actions. 1993;38 Spec No:C139-42. Miller TE, Dodd J, Ormrod DJ, Geddes R. Department of Medicine, University of Auckland School of Medicine, New Zealand. Previous laboratory based investigations of a commercially prepared freeze-dried extract of the NZ green-lipped mussel (Perna canaliculus) showed that the material had the capacity to inhibit experimentally induced inflammation.
6/1/1983 - Perna canaliculus in the treatment of rheumatoid arthritis
Caughey DE, Grigor RR, Caughey EB, Young P, Gow PJ, Stewart AW. Freeze-dried extracts of the New Zealand green lipped mussel, Perna canaliculus, have been promoted extensively as a treatment for rheumatoid arthritis for some years though there have been few published trials of its effectiveness.
12/19/1980 - Gastroprotective and anti-inflammatory properties of green lipped mussel (Perna canaliculus) preparation.
Arzneimittelforschung. 1980;30(12):2128-32. Rainsford KD, Whitehouse MW. Freeze-dried powdered preparations of whole (i.e. without shell) green-lipped mussel (Perna canaliculus) from New Zealand given orally to rats showed some modest anti-inflammatory activity (carrageenan paw oedema).
S. Brien, P. Prescott, B. Coghlan, N. Bashir and G. Lewith From the Department of Primary Care, University of Southampton, Aldermoor Health Centre, Aldermoor Close, Southampton, Hampshire, SO16 5ST and School of Mathematics, University of Southampton, University Road, Southampton, Hampshire SO17 1BJ, UK Abstract Complementary treatments for osteoarthritis (OA) are sought by patients for symptomatic relief and to avoid the iatrogenic effects of non-steroidal anti-inflammatories.
8/1/2007 - Novel anti-inflammatory omega-3 PUFAs from the New Zealand green-lipped mussel, Perna canaliculus
Comp Biochem Physiol B Biochem Mol Biol. 2007 Aug;147(4):645-56. Epub 2007 Apr 14 Treschow AP, Hodges LD, Wright PF, Wynne PM, Kalafatis N, Macrides TA. Natural Products Research Group, School of Medical Sciences, RMIT University, Bundoora, Victoria, 3083, Australia.
6/11/2007 - Immunomodulation of murine collagen-induced arthritis by N, N-dimethylglycine and a preparation of Perna canaliculus
BMC Complement Altern Med. 2007 Jun 11;7:20 Lawson BR, Belkowski SM, Whitesides JF, Davis P, Lawson JW. Department of Biological Sciences, Clemson University, Clemson, SC, USA.
6/1/2006 - Clinical efficacy and tolerance of an extract of green-lipped mussel (Perna canaliculus) in dogs presumptively diagnosed with degenerative joint disease
N Z Vet J. 2006 Jun;54(3):114-8 Pollard B, Guilford WG, Ankenbauer-Perkins KL, Hedderley D. Institute of Veterinary, Animal and Biomedical Sciences, Massey University, Private Bag 11222, Palmerston North, New Zealand.
1/13/2006 - In vitro modulation of inflammatory cytokine and IgG levels by extracts of Perna canaliculus
BMC Complement Altern Med. 2006 Jan 13;6:1 Mani S, Lawson JW. Department of Microbiology and Molecular Medicine, Clemson University, Clemson, SC 29634, USA. BACKGROUND: Inflammation is a predominant characteristic of autoimmune diseases which is characterized by the increased expression of pro-inflammatory cytokines.
6/1/2002 - Improvement of Arthritic Signs in Dogs Fed Green-Lipped Mussel (Perna canaliculus)
The American Society for Nutritional Sciences J. Nutr. 132:1634S-1636S, June 2002 Tiffany Linn Bierer3 and Linh M. Bui EXPANDED ABSTRACT Arthritis is a significant problem in both humans and animals that may occur at any age but is particularly common in older individuals.
9/1/2000 - Anti-inflammatory effects of a stabilized lipid extract of Perna canaliculus
Halpern GM. Allerg Immunol (Paris). 2000 Sep;32(7):272-8 University of California, USA. A lipid-rich extract, prepared by supercritical fluid (CO2) extraction of freeze-dried stabilized NZ green-lipped mussel powder (Lyprinol) has shown significant anti-inflammatory (AI) activity when given to animals and humans.
5/1/1993 - Anti-inflammatory activity of glycogen extracted from Perna canaliculus (NZ green-lipped mussel).
Agents Actions. 1993;38 Spec No:C139-42. Miller TE, Dodd J, Ormrod DJ, Geddes R. Department of Medicine, University of Auckland School of Medicine, New Zealand. Previous laboratory based investigations of a commercially prepared freeze-dried extract of the NZ green-lipped mussel (Perna canaliculus) showed that the material had the capacity to inhibit experimentally induced inflammation.
6/1/1983 - Perna canaliculus in the treatment of rheumatoid arthritis
Caughey DE, Grigor RR, Caughey EB, Young P, Gow PJ, Stewart AW. Freeze-dried extracts of the New Zealand green lipped mussel, Perna canaliculus, have been promoted extensively as a treatment for rheumatoid arthritis for some years though there have been few published trials of its effectiveness.
12/19/1980 - Gastroprotective and anti-inflammatory properties of green lipped mussel (Perna canaliculus) preparation.
Arzneimittelforschung. 1980;30(12):2128-32. Rainsford KD, Whitehouse MW. Freeze-dried powdered preparations of whole (i.e. without shell) green-lipped mussel (Perna canaliculus) from New Zealand given orally to rats showed some modest anti-inflammatory activity (carrageenan paw oedema).